Also Known As: Amphetamine/Dextroamphetamine, Adderall
Adderall is a brand name of amphetamine saltsâ€“based medication used for attention-deficit hyperactivity disorder and narcolepsy - legal only in the United States and Canada. It is a brand-name psychostimulant medication composed of racemic amphetamine aspartate monohydrate, racemic amphetamine sulfate, dextroamphetamine saccharide, and dextroamphetamine sulfate, which are all amphetamine salts. It is thought to work by increasing the amount of dopamine and norepinephrine in between synapses in the brain because the drug is a potent dopamine reuptake inhibitor and norepinephrine reuptake inhibitor. It is available in two formulations: IR (Instant Release) and XR (Extended Release). The immediate release formulation is indicated for use in Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy, while the XR formulation is approved for use only with ADHD.
Like other stimulant prescription drugs, Adderall directly affects the mesolimbic reward pathway in the brain. Amphetamine salts preparations are considered to have high abuse potential, and it is classified as Schedule II by the US DEA.