ZMapp is an experimental serum mixture of three humanized monoclonal antibodies for immunological protection against the Ebola virus.[1][2][3] On 31 July 2014 the drug was first tested on humans. It was administered to two Americans who had been infected with Ebola. Both patients appeared to have had positive results.[4][5]

The ZMapp drug is being developed by Mapp Biopharmaceutical Inc., a result of the collaboration between Mapp Biopharmaceutical (San Diego), LeafBio (the commercial arm of Mapp Biopharmaceutical), Defyrus Inc. (Toronto), the U.S. government and the Public Health Agency of Canada.[1] The antibody work came out of research projects funded by the U.S. Army more than a decade ago.[6] The Defense Threat Reduction Agency (DTRA) announced additional funds to Mapp Biopharmaceutical based on the "promising results".[7]

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