Also Known As: Vinblastine, Velban
Vinblastine is an antimicrotubule drug used to treat certain kinds of cancer, including Hodgkin's lymphoma, non-small cell lung cancer, breast cancer, head and neck cancer, and testicular cancer. It is also used to treat Langerhan cell histiocytosis. Vinblastine was traditionally obtained from Catharanthus roseus (Madagascar Periwinkle) as it was generated in the vinca plant by the joining of two alkaloids catharanthine and vindoline.
Vinblastine is a component of a number of chemotherapy regimens, including ABVD for Hodgkin lymphoma. It is also used to treat histiocytosis according to the established protocols of the Histiocytosis Association of America.