Also Known As: Librium, Chlordiazepoxide, Angirex, Klopoxid, Libritabs, Mesural, Multum, Novapam, Risolid, Silibrin, Sonimen, Tropium, Limbitrol
Chlordiazepoxide, is a sedative/hypnotic drug and benzodiazepine. It is marketed under the trade names Angirex, Klopoxid, Librax (also contains clidinium bromide), Libritabs, Librium, Mesural, Multum, Novapam, Risolid, Silibrin, Sonimen and Tropium.
Chlordiazepoxide was the first benzodiazepine to be synthesised and the discovery of chlordiazepoxide was by pure chance. Chlordiazepoxide and other benzodiazepines were initially accepted with widespread public approval but were followed with widespread public disapproval and recommendations for more restrictive medical guidelines for its use.
Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life. The drug has amnestic, anxiolytic, hypnotic and skeletal muscle relaxant properties.
Chlordiazepoxide is indicated for the short term (2–4 weeks) treatment of anxiety which is severe and disabling or subjecting the person to unacceptable distress. It is also indicated as a treatment for the management of acute alcohol withdrawal syndrome