Also Known As: Lyrica, Pregabalin

Pregabalin (INN) (Lyrica) and (Serigaptin) /prɨˈɡæbəlɨn/ is an anticonvulsant drug used for neuropathic painand as an adjunct therapy for partial seizures with or without secondary generalization in adults.[1] It has also been found effective for generalized anxiety disorder and is (as of 2007) approved for this use in the European Union.[1] It was designed as a more potent successor to gabapentin. Pregabalin is marketed byPfizer under the trade name Lyrica. Pfizer described in an SEC filing that the drug could be used to treat epilepsy, post-herpetic neuralgia, diabetic peripheral neuropathy and fibromyalgia. Sales reached a record $3.063 billion in 2010.[2]

Recent studies have shown that pregabalin is effective at treating chronic pain in disorders such as fibromyalgia[3] and spinal cord injury.[4] In June 2007, pregabalin became the first medication approved by the U.S. Food and Drug Administration specifically for the treatment of fibromyalgia.[5]

It is considered to have a low potential for abuse, and a limited dependence liability if misused, but is classified as a Schedule V drug in the U.S.[6]

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