Gemfibrozil

Also Known As: Gemfibrozil, Lopid, Gen-Fibro

Gemfibrozil is the generic name for an oral drug used to lower lipid levels. (treatment for high cholesterol) It belongs to a group of drugs known as fibrates. It is most commonly sold as the brand name, Lopid. Other brand names include Jezil and Gen-Fibro.

Is an activator of Peroxisome proliferator-activated receptor-alpha (PPARα), a nuclear receptor that is involved in metabolism of carbohydrates and fats, as well as adipose tissue differentiation. This increase in the synthesis of lipoprotein lipase thereby increases the clearance of triglycerides.

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