Also Known As: Terbutaline, Brethine, Bricanyl, Brethaire, or Terbulin
Terbutaline (trade names Brethine, Bricanyl, Brethaire, or Terbulin) is a B²2-adrenergic receptor agonist.
Terbutaline is currently on the World Anti-Doping Agency's list of prohibited drugs for Olympic athletes, except when administered by inhalation and a Therapeutic Use Exemption (TUE) has been obtained in advance.
Terbutaline is currently used to delay preterm labor for 48 hours to allow for fetal lung maturity through steroid injections. It should not be used to prevent preterm labor or delay labor past 48-72 hours. In February 2011, the Food and Drug Administration has ordered to put a boxed warning on the drug's label. Pregnant women should not be given injections of the drug terbutaline for the prevention of preterm labor or for long-term (beyond 48-72 hours) management of preterm labor, and should not be given oral terbutaline for any type of prevention or treatment of preterm labor "due to of the potential for serious internal heart problems and death." It has also been used to treat asthma related conditions.
The American College of Obstetricians and Gynecologists also discourages the use of terbutaline for preventing preterm labor.