Accutane

Also Known As: Accutane, Isotretinoin, Roaccutane, Amnesteem, Claravis, Sotret

Isotretinoin, INN, is a medication used mostly for cystic acne. It was first developed for brain, pancreatic and other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. Its effects are systemic and nonselective. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body.

Isotretinoin's best-known and most dangerous side effect is birth defects. This is because of the molecule's close resemblance to retinoic acid, a natural vitamin A derivative which controls normal embryonic development. Because of this, it is one of the most difficult pharmaceuticals to obtain in the United States.

The most common brands are Roaccutane (Hoffman-La Roche, known as Accutane in the United States before July 2009), Amnesteem (Mylan), Claravis (Barr), or Sotret (Ranbaxy)..

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Average Effectiveness

This is the Average effectiveness per ailment as reported by our participants (you).

Effectiveness:
  • 0 = No improvement or Worse
  • 1 = Slight improvement
  • 2 = Moderate Improvement
  • 3 = Significant Improvement
  • 4 = Cured

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